Tag nrho cov txheej txheem ntawm khov-kom qhuav los ntawm khov-kom qhuav tshuab: pre-khov, nrawm nrawm thiab nqus qhuav.
1. Pre-khov thiab khov khov
Thaum lub tshuab nqus khov ua ke ua cov khoom khov-qhuav, nws yuav tsum xub ua ntej khov hauv qab lub crystallization kub, qhov ntawd yog, solution) uas tsim cov ntaub ntawv yuav tsum khov ua ntej. Qhov laj thawj rau kev coj los ua kom khov khov kho yog tias kev nrawm dua ntawm khov kho, cov roj khov me me hauv cov zaub mov, thiab cov khoom siv tsawg dua rau cov hlwb.
2. Lub Tshuab Kom Qhuav
Lub tshuab ziab hauv Lyophilizer ua kom qhuav-qhuav yog feem ntau muab faib ua ob: thawj ziab thiab nqus kom qhuav. Lossis sublimation kom qhuav thiab tshuaj ntsuam kom qhuav yuav siv tau.
1) ib-zaug ziab
Tom qab khov ua ntej, cov dej khov yuav tsum tau muab tshem tawm ntawm cov ntaub ntawv los ntawm sublimation, thiab ob qho tsis xav tau tswj hwm: kub thiab siab. Thaum cov khoom siv cua sov nyob hauv qab lub tshuab nqus dej, cov muaj roj yuav sublast rau hauv dej vapor thiab txeej los ntawm cov khoom. Tus nqi sublimation nyob ntawm qhov sib txawv ntawm cov vapor siab ntawm cov khoom siv thiab cov khoom siv vapor. Cov lwg me me yuav txav los ntawm cov qauv siab uas muaj nqis rau cov qauv tsawg-siab. Vim tias lub vapor siab muaj feem xyuam rau qhov kub thiab txias, cov khoom kub yuav tsum yog siab dua li cov dej khov ntxiab ntsuas kub.
2) Lub tsev kom qhuav
Tom qab thawj zaug ziab, tag nrho cov dej khov rau hauv cov khoom tau sublimated, tab sis tseem muaj qee yam kua hauv cov khoom, yog li nws yog qhov tsim nyog kom qhuav rau dej tag nrho cov dej. Cov txheej txheem no tseem hu ua isotothermal desorption, thiab dej dhau heev yuav xav tau los ntawm qhov kub thiab txias.